250 BCCenturies: 4th century BC - 3rd century BC - 2nd century BC
- Bactria gains its independence from the Seleucid Empire. (approximate date)
- Antiochus II Theos makes peace with Ptolemy II of Egypt.
- Xiao Wen Wang becomes King of the Qin Dynasty of China but dies before the end of the year.
- First Punic War: Lucius Caecilius Metellus captures 140 war elephants in Sicily, transports them to Rome and displays them in the Circus Maximus.