The Kinase reference article from the English Wikipedia on 24-Jul-2004 (provided by Fixed Reference: snapshots of Wikipedia from wikipedia.org)

Kinase

In biochemistry, a kinase is a type of enzyme that transfers phosphate groups from, for example, ATP to a specified substrate or target; the process is termed "phosphorylation". Typically, the target is "activated" or "energized" by being phosphorylated. All kinases require a divalent metal ion such as Mg²⁺ or Mn²⁺ to transfer the phosphoryl group.

There are many different types of kinases; each named for the target substrate. Some notable kinases are:

• Protein kinase (see there for more details);
• Janus kinase;
• Tyrosine kinase;
• Focal adhesion kinase;
• Creatine kinase;
• Pyruvate kinase;
• Hexokinase.

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