The Rosemary Kennedy reference article from the English Wikipedia on 24-Jul-2004
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Rosemary Kennedy

Time you got around to sponsoring a child
Rosemary Kennedy (born September 13, 1918) is the oldest daughter of Rose and Joseph P. Kennedy, Sr

Rosemary was born slightly retarded. The family had problems dealing with this, and in 1941 her father asked a neurosurgeon to perform a prefrontal lobotomy — this was considered a magical cure. This did not have the effect that was foreseen, and afterwards Rosemary was incapable of living a normal life. She has been living in an institution in Wisconsin since that time.

See also: List of well-known U.S. presidential relatives