The Yeast artificial chromosome reference article from the English Wikipedia on 24-Jul-2004
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Yeast artificial chromosome

Helping orphans the way you would do it
A yeast artificial chromosome (short YAC) is a vector used to clone large DNA fragments (up to 400 kb). It is an artificially constructed chromosome and contains the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells.

See also : plasmid, cosmid